Betting Content

Last Chance San Fran Fans: Bet $5, Get $200 Promo for SF-KC Expires Today!

San Francisco Fans: Get $200 Bonus if Your Team Wins

Super Bowl 58 odds: 49ers open up as slight favorites vs. Chiefs

49ers vs. Lions: NFC Championship game injury report, weather, betting odds, TV and streaming info

Jan 20, 2024; Santa Clara, CA, USA; San Francisco 49ers running back Christian McCaffrey (23)

49ers Super Bowl odds: San Francisco survives scare, remain Super Bowl favorites

San Francisco 49ers defensive end Nick Bosa (97)

49ers vs. Packers playoff game today: Game time, injury report, odds, TV and streaming info

NFL FanDuel Sportsbook Promo: Win $150 GUARANTEED Betting $5 on 49ers vs. Packers!

San Francisco 49ers quarterback Brock Purdy (13)

2024 NFL playoffs: 49ers should wallop Packers in divisional round (because odds say so)

Baltimore Ravens quarterback Lamar Jackson (8)

Latest betting odds suggest 49ers will face this team in Super Bowl 58

San Francisco 49ers wide receiver Deebo Samuel (19)

49ers vs. Rams Week 18 game time, location, TV channel and streaming, odds and more

San Francisco 49ers v Washington Redskins

49ers game today vs. Commanders: Week 17 injury report, odds, weather, TV channel and live stream

Dec 25, 2023; Santa Clara, California, USA; San Francisco 49ers running back Christian McCaffrey

49ers vs. Commanders prediction, odds, spread, injuries, trends for NFL Week 17

San Francisco 49ers v Washington Redskins

49ers vs. Commanders: Week 17 game time, location, betting odds, TV channel and streaming

San Francisco 49ers quarterback Brock Purdy (13)

Brock Purdy MVP odds take nosedive after 4-interception outing vs. Ravens

Dec 17, 2023; Glendale, Arizona, USA; San Francisco 49ers wide receiver Deebo Samuel (19) celebrates

Monday Night Football best anytime touchdown scorer picks for Ravens vs. 49ers

Baltimore Ravens v San Francisco 49ers

49ers vs. Ravens: Monday Night Football game time, location, odds, TV and streaming

Dec 10, 2023; Santa Clara, California, USA; San Francisco 49ers quarterback Brock Purdy (13) is

NFL MVP Odds: Brock Purdy skyrockets to odds on favorite for MVP

San Francisco 49ers quarterback Brock Purdy (13)

Brock Purdy back as betting-odds favorite for MVP after 49ers throttle Cardinals

San Francisco 49ers defensive end Nick Bosa (97) pressures Arizona Cardinals quarterback Kyler Murray (1)

49ers game today vs. Cardinals: Week 15 injury report, betting odds, TV and streaming

San Francisco 49ers v Arizona Cardinals

49ers vs. Cardinals: Week 15 game time, location, TV and streaming, odds and more: Everything you need to know

San Francisco 49ers wide receiver Brandon Aiyuk

Seahawks vs. 49ers best anytime scorer picks (bet on Brandon Aiyuk)

San Francisco 49ers wide receiver Deebo Samuel (19)

Seahawks vs. 49ers prediction, odds, spread, injuries, trends for NFL Week 14

Seattle Seahawks quarterback Geno Smith (7) passes against the San Francisco 49ers

49ers vs. Seahawks time, location, TV and streaming, odds and more: Everything you need to know

Dec 3, 2023; Philadelphia, Pennsylvania, USA; San Francisco 49ers running back Christian McCaffrey

49ers leap to massive favorite in latest odds to win the Super Bowl

San Francisco 49ers quarterback Brock Purdy (13)

You won't believe Brock Purdy MVP odds after 49ers wallop Jalen Hurts, Eagles

San Francisco 49ers defensive end Nick Bosa (97)

49ers game today vs. Eagles: Week 13 injury report, betting odds, TV channel and live stream

Nov 19, 2023; Santa Clara, California, USA; San Francisco 49ers tight end George Kittle (85) reacts

Best NFL prop bets for 49ers vs. Eagles in Week 13

Nov 23, 2023; Seattle, Washington, USA; San Francisco 49ers quarterback Brock Purdy (13) reacts

49ers Super Bowl odds make major move following Week 12's action