SF 49ers Injuries

San Francisco 49ers safety Malik Mustapha (6)

Devastating injury to key player put 49ers in a bind entering 2025 NFL Draft

Christian McCaffrey injury update is music to 49ers' fans ears

49ers get a glimmer of hope with Brandon Aiyuk injury update

Brandon Aiyuk injury update reveals why 49ers won't be able to trade him

Seattle Seahawks v San Francisco 49ers

Christian McCaffrey injury update is music to 49ers fans' ears

San Francisco 49ers running back Isaac Guerendo (49)

49ers running back sure seems like it's become the riskiest position in sports

Detroit Lions vs. San Francisco 49ers

Injuries prompt 49ers to deploy makeshift offensive line vs. Lions

San Francisco 49ers linebacker Dre Greenlaw (57)

Dre Greenlaw suffers injury vs. Dolphins: Latest news and updates

San Francisco 49ers running back Isaac Guerendo (31)

Is Isaac Guerendo playing today? Full injury update for 49ers running back

San Francisco 49ers running back Isaac Guerendo (31)

49ers' final injury report vs. Dolphins: Bad news for RB Isaac Guerendo

San Francisco 49ers running back Isaac Guerendo

Updated 49ers depth chart: Who is Isaac Guerendo's backup?

Los Angeles Rams v San Francisco 49ers

49ers' comically bad injury luck gets worse with Isaac Guerendo update

San Francisco 49ers left tackle Trent Williams (71)

49ers on the brink of losing yet another All-Pro for rest of the season

San Francisco 49ers, Isaac Guerendo

Is Isaac Guerendo playing tonight? Latest injury update for TNF

San Francisco 49ers linebacker Dre Greenlaw

Dre Greenlaw's long-awaited return might potentially save 49ers' season

San Francisco 49ers left tackle Trent Williams (L) and defensive end Nick Bosa (R)

49ers injury report vs. Bears: Niners winless without Nick Bosa, Trent Williams

San Francisco 49ers running back Jordan Mason (24) avoids a tackle by Buffalo Bills cornerback Rasul Douglas (31)

49ers slammed with even more brutal injury news after loss to Bills

San Francisco 49ers running back Christian McCaffrey (23)

Christian McCaffrey injury comes at the absolute worst time vs. Bills

San Francisco 49ers quarterback Brock Purdy (13)

Is Brock Purdy playing today vs. Packers? Full injury update for 49ers QB

San Francisco 49ers quarterback Brock Purdy (13)

Final Week 12 injury report spells worst-case disaster for 49ers

San Francisco 49ers quarterbacks Joshua Dobbs (L), Brandon Allen (C) and Brock Purdy (R)

Brock Purdy injury raises doubts on 49ers' backup quarterback situation

San Francisco 49ers quarterback Brock Purdy (13)

Latest Brock Purdy injury news paints grim picture for 49ers

San Francisco 49ers defensive end Nick Bosa (97)

49ers desperately cling to hope Nick Bosa is healthy enough for Packers game

San Francisco 49ers Nick Bosa (97). Mandatory Credit: David Gonzales-Imagn Images

49ers' loss to Seahawks proves Nick Bosa is more vital than we think

San Francisco 49ers v Tampa Bay Buccaneers

49ers gameday versus Seahawks starts with bad injury news on George Kittle

San Francisco 49ers tight end George Kittle (85)

Is George Kittle playing today vs. Seahawks? Latest injury updates for 49ers TE

San Francisco 49ers left tackle Trent Williams (71)

49ers must consider resting injured Trent Williams vs. Seahawks

San Francisco 49ers tight end George Kittle (L) and defensive end Nick Bosa (R)

Final 49ers injury report for Week 11 lists too many starters for comfort