49ers injury news: Trent Williams, Javon Hargrave questionable vs. Jaguars

San Francisco 49ers left tackle Trent Williams (71)
San Francisco 49ers left tackle Trent Williams (71) / Thearon W. Henderson/GettyImages

1 p.m. ET. 42. Fox. Sunday, Nov. 12. 6-2. 49ers -3. 5-3. 49ers-Jaguars preview. 52

The 49ers could still be missing two key cogs in the trenches for their Week 10 road game against the Jaguars this Sunday.

There's no doubting the San Francisco 49ers needed a bye in Week 9.

From a rest perspective, the Niners hope that a one-week break will give a new focus after a three-game losing streak. And from a health perspective, it's hopeful the added time off will afford any players who are banged up can heal and be closer to 100 percent.

One of San Francisco's best players, wide receiver Deebo Samuel, will be back from a two-game absence stemming from a shoulder injury suffered back in Week 6.

Samuel's return is a boost for an offense that has struggled to reach 20 points over the losing streak after habitually scoring 30-plus over the five games prior.

But that doesn't mean the 49ers will be at 100 percent when they travel to take on the 6-2 Jacksonville Jaguars this Sunday.

Trent Williams, Javon Hargrave part of lengthy 49ers injury report vs. Jaguars

In the same game that Samuel suffered his injury, All-Pro left tackle Trent Williams suffered an injury to his ankle. Despite returning to that game, he'd miss the subsequent two and was replaced by swing tackle Jaylon Moore in Weeks 7 and 8.

While Williams was back at practice ahead of Sunday, head coach Kyle Shanahan told reporters that the veteran lineman would be a game-time decision and is listed as questionable on the team's Week 9 injury report.

Meanwhile, left guard Aaron Banks and defensive end Drake Jackson will be out, while starting defensive tackle Javon Hargrave is a bit of a surprise addition with a knee injury, and he'll be questionable as well Williams.

Defensive end Robert Beal Jr. and cornerbacks Samuel Womack and Darrell Luter Jr. all had practice windows opened after starting the season on injury lists (or on injured reserve after one week, in Womack's case).

Those three are listed as questionable, too.

The Niners and Jags kick off on Sunday, Nov. 12 at 1 p.m. ET from TIAA Bank Field in Jacksonville, Florida.

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