The back end of the San Francisco 49ers' 90-man training camp roster seems to be a wild place to be.
True, the Niners are dealing with a significant number of soft-tissue injuries in the opening weeks of camp, including wide receivers Jauan Jennings, Ricky Pearsall and Jacob Cowing all missing various amounts of time.
That's led to general manager John Lynch and head coach Kyle Shanahan bringing in several players on tryouts, signing some and often releasing them mere days later.
Just ask wide receiver Quintez Cephus.
With rookie running back Jordan James seemingly dealing with an injury, too, Lynch and Shanahan responded on Thursday by signing running back Ameer Abdullah and wide receiver Andy Isabella, first reported by Fox Sports insider Jordan Schultz.
But that was just the opening line of San Francisco's transactions.
49ers execute a swarm of back-end roster moves to aid injury concerns
Abdullah and Isabella weren't the only two moves the 49ers pulled off.
According to NBC Sports Bay Area's Matt Maiocco, the Niners also signed quarterback Carter Bradley and wide receiver Marquez Callaway. They also activated offensive lineman Ben Bartch, who opened up camp on the non-football injury list.
To make room for the new bodies, San Francisco cut the recently signed wide receiver, Equanimeous St. Brown, and parted ways with offensive lineman Sebastian Gutierrez, wide receiver Malik Knowles and safety Jaylen Mahoney.
The 49ers signed RB Ameer Abdullah, QB Carter Bradley, WR Marquez Callaway and WR Andy Isabella and cut WR Equanimeous St. Brown, OL Sebastian Gutierrez, WR Malik Knowles and S Jaylen Mahoney. The team also activated OL Ben Bartch off the NFI list.
— Matt Maiocco (@MaioccoNBCS) July 31, 2025
Mahoney's departure is a small surprise, as he saw modest action last season and figured to be a strong darkhorse candidate to carve out a niche role on the regular-season 53-man roster, particularly with the concerns the 49ers have regarding safety depth.
If there's any solace, the bulk of these signings and departures merely help round out their respective positions' depth charts, ensuring enough bodies are present to participate in practices and during preseason games, which kick off next week.
However, if injuries remain to key players like Jennings, the concern becomes far more alarming.