49ers game today: 49ers vs. Titans injury report, spread, over/under, schedule, live stream, TV channel

The 49ers visit the Titans on Thursday Night Football, and Niner Noise brings you the latest injury reports, betting odds and how you can tune in live.

While the San Francisco 49ers can’t feel overly good about having to travel two time zones to the east on a short week to face off against the Tennessee Titans on Thursday Night Football in a game that could have serious playoff implications for both teams, at least the Niners can take comfort knowing they’re on a hot streak while the Titans aren’t.

Tennessee is coming off an ugly road loss at the hands of the Pittsburgh Steelers and has lost three of its last four games, seeing its once commanding hold on the AFC playoff picture slip away.

Meanwhile, San Francisco has won five of its last six games and is in a position to climb even higher than the No. 6 seed in the NFC playoff seeding.

Turnovers, always a higher possibility on a short week, could prove to be the difference, too, and the 49ers have climbed up from minus-9 earlier this season in turnover differential to minus-2, whereas the Titans have slipped to minus-7.

Perhaps that’s an X-factor, too.

49ers injury report vs. Titans Week 16

Short weeks are always challenging, but the Niners may be seeing some reinforcements come back off injuries, although the following players were still listed on the team’s Week 16 injury report:

• LB Dre Greenlaw (groin): OUT
• S Talanoa Hufanga (knee): OUT
• DL Maurice Hurst (calf): OUT
• RB Elijah Mitchell (knee): OUT
• LB Azeez Al-Shaair (elbow): Questionable

Mitchell, who missed two games with a concussion and knee injury, might have been close to returning, but it appears as if Jeff Wilson Jr. will get the start after rushing for over 100 yards and a touchdown in Week 15.

Meanwhile, the Titans have been without wide receiver A.J. Brown (chest) and could potentially be without fellow wideout Julio Jones (hamstring), too, but both could suit up according to the latest injury notes.

49ers vs. Titans odds, spread, over/under & betting pick Week 16

San Francisco’s opening spread for Week 16 was minus-3, and that spread increased half a point to minus-3.5 before going down again to minus-3, according to the oddsmakers over at WynnBET. Perhaps Tennessee’s injury woes influenced the move, but it’s certainly refreshing to see head coach Kyle Shanahan’s squad favored more.

The Niners’ moneyline currently sits at minus-180, whereas the Titans are at plus-160. The over/under for the game is 44.5.

Our initial prediction suggested a 24-20 win for Tennessee, but given the Titans’ injuries and the fact the Niners seem to be getting healthier, let’s go ahead and buck the road-team short-week narrative and dish out a new prediction, suggesting a 21-17 San Francisco victory.

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What channel is the 49ers game on Week 16?

This will mark the final prime-time nationally televised game the Niners will play this season, and fans across the country can tune in by turning the dial to NFL Network when both teams kick off on Thursday, Dec. 23 at 8:20 p.m. at Nissan Stadium in Nashville, Tennessee.

Kevin Burkhardt will be on the play-by-play duties, while Greg Olsen will handle color commentary. Pam Oliver will be on the sidelines.

49ers vs. Titans live stream

For those who don’t have television access to NFL Network and/or would rather stream the game, 49ers.com will stream the game live, and the team’s official app can also be downloaded. Both options are for in-market fans only.

Additionally, fuboTV offers a free seven-day trial for first-time users.

49ers next game and schedule

San Francisco will have only two regular-season games left after heading to Nashville, the first being what should be viewed as a very winnable contest at home at Levi’s Stadium versus the Houston Texans.

Then, the Niners finish off the regular season by visiting their NFC West rivals, the Los Angeles Rams, in Week 18.

• Week 17 vs. Houston Texans: Sunday, Jan. 2 at 4:05 p.m. ET
• Week 18 @ Los Angeles Rams: Sunday, Jan. 9 at 4:25 p.m. ET