Eagles vs. SF 49ers: 5 players who’ll tear up Philly’s defense

Brandon Lloyd #84 of the San Francisco 49ers covered by Cary Williams #26 of the Philadelphia Eagles (Photo by Ezra Shaw/Getty Images)
Brandon Lloyd #84 of the San Francisco 49ers covered by Cary Williams #26 of the Philadelphia Eagles (Photo by Ezra Shaw/Getty Images) /
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George Kittle, SF 49ers
San Francisco 49ers tight end George Kittle (85). Mandatory Credit: San Francisco 49ers/Pool Photo via USA TODAY Network /

No. 1: SF 49ers Tight End George Kittle

With all the secondary shuffling the Eagles will likely have to employ this Sunday, one of the other ramifications working in the SF 49ers’ favor, aside from Brandon Aiyuk potentially going off, is tight end George Kittle winding up being a major impact player.

Kittle, who missed Weeks 2 and 3 with a knee injury suffered in the season opener, finally returned to practice in full this week and is expected to be a full go for Sunday’s contest.

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That’s great news for San Francisco, and it’s for multiple reasons.

But the biggest will be his impact in the receiving game, particularly as one of Nick Mullens’ favorite targets. According to Pro Football Focus, Mullens boasted a passer rating of 107.8 when targeting Kittle.

Yeah, that’s pretty good.

The other element, too, is Jalen Mills. Mills, so far on the season, is allowing opposing quarterbacks to post a 118.8 passer rating when targeting him in coverage.

Based on those two analytical numbers, the Kittle-Eagles matchup looks to be one highly weighed in the Niners’ favor.

It’s been a while since Kittle had one of those dominant games, but fans should expect him to go off against a struggling Philadelphia squad that’ll have more than enough problems trying to cover both him and Aiyuk.

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The SF 49ers and Eagles kick off their Sunday Night Football Week 4 matchup on Oct. 4 at 8:20 p.m. ET.