Who is playing Thursday Night Football for Week 3?

The 49ers and Giants square off for the Niners' 2023 home opener, and it'll be on the bright-light short week of Thursday Night Football.

There probably aren't too many teams that actually enjoy playing on the short week that is Thursday Night Football, unless that team enjoyed a bye the week before.

At this point in the season with just two weeks of football under the belt, no one is partaking in any byes just yet.

However, if one of those teams either stays home on the short week or doesn't have to travel too far for Thursday night (or from the previous week), things aren't too bad.

In Week 2, the Philadelphia Eagles showed why they're top NFC contenders this season in a 34-28 slugfest with the Minnesota Vikings on Thursday Night Football.

One of Philly's top threats to getting back to the Super Bowl, the San Francisco 49ers, will be featured this week on Thursday night.

Thursday Night Football Week 3 will feature NY Giants at 49ers

The Niners will be playing their home opener on Thursday Night Football after being on the road and defeating both the Pittsburgh Steelers and Los Angeles Rams in Weeks 1 and 2, respectively.

Coming to visit San Francisco for the primetime game, the 1-1 New York Giants hope to bring some of the momentum from their improbable comeback victory on the road over the 49ers' NFC West rivals, the Arizona Cardinals, on Sunday.

Related story: How to watch every 49ers game this season with (or without) cable TV

The Niners opened up as 10-point home favorites for the game, according to the oddsmakers over at DraftKings, and it's possible the G-Men are without Pro Bowl running back Saquon Barkley, who likely suffered a sprained ankle at Arizona but avoided major injury despite the serious scare.

That benefits San Francisco, which will look to Week 3 to improve to a perfect 3-0 on the season.

The 49ers and Giants kick off on Thursday, Sept. 21 at 8:20 p.m. from Levi's Stadium in Santa Clara, California.

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