Is Deebo Samuel Playing Tonight? Latest Injury Update for 49ers vs. Cowboys in Week 5

The 49ers offense has done no wrong this season. Christian McCaffrey is the front runner for Offensive Player of the Year, Brock Purdy hasn't thrown an interception, and Deebo Samuel has looked dangerous once again as a do-it-all weapon.

However, Samuel has been dealing with a knee injury that is reportedly keeping him from being 100% heading into the 49ers primetime matchup on Sunday Night Football against the Dallas Cowboys in a battle of two of the top teams in the NFC.

Samuel has been on a tear this season, but now may be compromised. Here's the latest on the Niners wide out.

Deebo Samuel Injury Status for Week 5 Game Against Cowboys

Samuel is going to play in this one, but his knee is keeping him from being at his best, per ESPN's Ed Werder and NFL Network's Ian Rappaport.

I’ve been told that #49ers WR Deebo Samuel is improved but still not 100 percent because of the knee injury. He will undoubtedly play, the question is how much will he contribute?

He played 48 snaps last week but without a reception or target and just three touches.
— Ed Werder (@WerderEdESPN) October 8, 2023

From @GMFB: For the Sunday night game, #Cowboys standout defender Micah Parson (knee) and #49ers standout offensive weapon Deebo Samuel (knee) will both be at less than 100%. pic.twitter.com/4KhkbtqfAE
— Ian Rapoport (@RapSheet) October 5, 2023

Samuel dealt with injuries for much of last season that kept down his production, and after a hot start to 2023, he may be in trouble of slowing down yet again with this lingering injury.

While his effectiveness may be in question, Samuel hasn't missed practice all week. He was a limited participant on Wednesday and Thursday and practiced in full on Friday.

Best Deebo Samuel Prop Bet for 49ers vs. Cowboys in Week 5

Deebo Samuel OVER 50.5 Receiving Yards

While there may be some concern about Samuel heading into this matchup, I have to trust him to go over this number. After seeing a limited number of snaps against the Cardinals, I expect to Samuel to return to his similar target share, even if he isn't 100%.

In the three games prior to Week 4, Samuel cleared this number with relative ease, posting receiving yard totals of 55, 63, 129 to start the season.

I'm going to have faith in this 49ers offense to find its star receiver and for him to play a role in this one. Simply put, this number is now too low after a quiet outing in Week 4.

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Deebo Samuel Injury History

Dec. 2022: MCL Sprain, Ankle Sprain -- missed three games
Oct. 2022: Hamstring Stain -- missed one game
Jan. 2022: Knee Strain -- missed no games
Nov. 2021: Groin Strain -- missed one game
Nov. 2021: Calf Strain -- missed no games
Dec. 2020: Thigh Strain -- missed three games
Oct. 2020: Thigh Strain -- missed three games
June 2020: Foot Fracture -- missed three games
Oct. 2019: Groin Strain -- missed one game
Sept. 2016: Thigh Strain -- missed three games
Sept. 2015: Thigh Strain -- missed seven games

When is Debo Samuel Coming Back?

Samuel hasn't missed a game this season, and won't miss this marquee matchup in Week 5, but this is an effectiveness question for the jack-of-all-trades. Samuel didn't receiver a target nor a rush in last week's game against the Cardinals. However, after not missing practice all week, could he be in line for more porduction on Sunday Night Football?

49ers Next 5 Opponents

at Browns, Sunday, Oct. 15
at Vikings, Monday, Oct. 23
Bengals, Sunday, Oct. 29
at Jaguars, Sunday, Nov. 12
Buccaneers, Sunday, Nov. 19

49ers Injury Report

RB, Elijah Mitchell, Knee, OUT

Cowboys Injury Report

TE, Peyton Hendershot, Ankle, OUT
LB, Damone Clark, Shoulder, Questionable

Game odds refresh periodically and are subject to change.

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