5 bold Super Bowl predictions for San Francisco 49ers vs. Kansas City Chiefs

Prediction No. 2: Deebo Samuel will have his biggest influence as a running back, not a wide receiver

If the Niners are going to win the Super Bowl, then undoubtedly they're going to need to attack the Chiefs' one big weakness in their surprisingly weak run defense.

The 49ers have had problems with run defense in their own right in the second half of the year, but the Chiefs have somehow been even worse throughout the season to be one of the worst when it comes to defending the run.

The primary weapon to attack this, of course, will be the amazing Christian McCaffrey, who just finished third in MVP voting and was awarded Offensive Player of the Year. Having the best running back in the business gives the 49ers a leg up.

But then there's also Deebo Samuel, the Swiss Army knife that surely has to be due for a big game. With the Chiefs possessing an excellent pass defense led by two All-Pro cornerbacks in L'Jarius Sneed and Trent McDuffie, Deebo might find it hard to have a huge influence in the passing game.

No doubt, head coach Kyle Shanahan will dial up plays to get Deebo the ball. We all know the versatility Samuel possesses with his ability to run jet sweeps, reverses and out of the backfield as well as anyone else in the NFL.

He's the most versatile weapon in the league.

Given the Chiefs have a weakness against the run, look for Deebo to inflict his greatest damage on the Chiefs when he's handed the ball.