49ers vs. Steelers Week 1 game time, location, betting odds and how to watch live

The regular season is finally upon us, and 49ers games will begin to count this Sunday.
San Francisco 49ers v Pittsburgh Steelers
San Francisco 49ers v Pittsburgh Steelers / Michael Zagaris/GettyImages

0-0. 55. 1 p.m. ET. 0-0. 42. Fox. Sunday, Sept. 10. 49ers Steelers. 49ers -2.5

The 49ers kick off their 2023 regular-season campaign on the road against the Steelers, and we've got everything you need to know right here.

The San Francisco 49ers aren't too fond of the last time they had to travel to take on the Pittsburgh Steelers.

It was back in 2015, during the one-and-done Jim Tomsula year, and the Niners were walloped 43-18 in what turned into an omen for what would be a dreadful two-year stretch of bad football for the red and gold with two different head coaches.

Now, entering 2023, San Francisco is a Super Bowl contender under head coach Kyle Shanahan and will look to avoid some of the slow starts that have historically plagued Shanahan since he took over the franchise in 2017.

Always a playoff contender under head coach Mike Tomlin, the Steelers figure to be a tough Week 1 opponent for the 49ers.

When and where are the 49ers playing the Steelers Week 1?

The Niners and Steelers kick off their Week 1 matchup on Sunday, Sept. 10 at 1 p.m. ET from Acrisure Stadium (formerly Heinz Field) in Pittsburgh, Pennsylvania.

Bettings odds for 49ers-Steelers Week 1

Currently, according to the oddsmakers over at FanDuel, San Francisco is a 2.5-point road favorite over Pittsburgh.

The 49ers' moneyline is -142, and the Steelers' is +120. The over/under for the game is 40.5.

Game odds refresh periodically and are subject to change.

How to watch or stream the 49ers game vs. Steelers Week 1

Fox will broadcast Sunday's contest between the Niners and Steelers.

Joe Davis will do play-by-play commentary, while Daryl Johnson will add color commentary. Pam Oliver will be on the sideline.

Read more: 5 reasons to be nervous about the Niners in 2023

For those wishing to stream the game, in-market fans can go to 49ers.com or download the official 49ers app.

Additionally, fuboTV offers a free seven-day trial for first-time users.

Read more from Niner Noise