The 49ers are back after the bye week, and they'll face off against a surging Jaguars team that is infinitely better than the last time these to teams met.
The Jacksonville Jaguars aren't a team that usually winds up squaring off against the San Francisco 49ers, as there have been only six bouts between them in the all-time series, with the Niners winning four of those games.
However, San Francisco did travel out to north Florida back in 2021 and upended the Jags 30-10 in what was one more embarrassment for Urban Meyer during his brief but tumultuous stay as Jacksonville's one-and-done head coach.
That was then. This is now, though.
At 6-2, and riding a five-game win streak, the Jaguars are trending in the opposite direction as the struggling 49ers, who have lost three in a row. And never mind the fact the Niners are coming off their bye week and will have both extra rest and preparation.
The Jags also had their bye in Week 9. So, the only difference on that front is San Francisco will have to travel across the country to take on quarterback Trevor Lawrence and a rested Jacksonville team.
When and where is the 49ers game against the Jaguars, Week 9?
The 49ers and Jaguars square off against each other on Sunday, Nov. 12 at 1 p.m. ET.
The game will be played at TIAA Bank Field, home of the Jags.
What TV channel will the 49ers and Jaguars game be on?
Fox will broadcast Sunday's game between Jacksonville and San Francisco.
The coverage area for the game isn't known yet, but 506 Sports is an excellent resource for both coverage maps and revealing who will handle both play-by-play and color commentary duties.
How to stream the 49ers and Jaguars game
fuboTV offers a free seven-day trial for first-time users.
49ers vs. Jaguars odds, moneyline and over/under
Despite each team's respective streaks, the oddsmakers at FanDuel are opening up with the Niners as 2.5-point road favorites.
San Francisco's moneyline is -146, while Jacksonville's is +124.
The over/under for the game is 44.5.
Game odds refresh periodically and are subject to change.