49ers game today vs. Browns: Injury report, weather, odds, TV channel and live stream

Sunday, Oct. 15. 49ers-Browns gameday. 2-2. 53. 42. Fox. 49ers -9.5. 1 p.m. ET. 5-0

The 49ers are back on the road today against the Browns from Cleveland, and we've got your how-to-watch info right here.

On the surface, the San Francisco 49ers shouldn't have too much difficulty improving to 6-0 despite taking to the road and facing a .500 Cleveland Browns team without quarterback Deshaun Watson (shoulder) available.

But games aren't always played on the surface.

Cleveland is coming off a bye week, and despite starting veteran journeyman P.J. Walker under center, it can turn to a top-three defense that'll look to make life difficult for Niners quarterback Brock Purdy and Co.

Plus, with San Francisco coming off a primetime domination of the Dallas Cowboys last Sunday night, Week 6 on the road is setting up to be a potential trap game.

Unless the 49ers defense, which flustered Dallas for almost all of Week 5, does the same and more to Walker on Sunday.

Let's break down everything you'll want to know for this NFC West versus AFC North matchup.

49ers vs. Browns injury report Week 6

The Niners have just two players appearing on Week 6's injury report:

LB Dre Greenlaw (hamstring): Questionable
RB Elijah Mitchell (knee): Questionable

Mitchell has missed the last two games with his injury, and it'd be second-year pro Jordan Mason getting the bulk of second-string carries behind the starter, Christian McCaffrey, if Mitchell isn't available.

Cleveland, meanwhile, will be without Watson and also All-Pro guard Joel Bitonio (knee).

Tight end David Njoku (face, hand) and center Ethan Pocic (chest, knee, foot) are also questionable.

When and where will the 49ers vs. Browns game be played?

The Browns are playing hosts to San Francisco in Week 6, and the game will kick off on Sunday, Oct. 15 at 1 p.m. ET from Cleveland Browns Stadium in Cleveland, Ohio.

What's the NFL weather going to be like for 49ers vs. Browns?

The forecast calls for a kickoff temperature of 54 degrees Fahrenheit and cloudy with a 57-percent chance of rain showers, and the wind is going to be northwesterly at 16 miles per hour.

49ers vs. Browns betting odds, spread, over/under for Week 6

The 49ers originally opened as 4.5-point road favorites in the game, according to the oddsmakers at FanDuel.

However, with the news that Watson would be out, the spread jumped to 9.5 points in favor of the Niners, and their moneyline is now -590, whereas Cleveland's is +440.

The over/under for the game is 35.5.

Game odds refresh periodically and are subject to change.

49ers vs. Browns TV channel broadcast

Fox will broadcast Sunday's contest between San Francisco and Cleveland.

Kevin Burkhardt will handle play-by-play duties, while Greg Olsen will provide color commentary. Erin Andrews and Tom Rinaldi will be on the sidelines.

All of the West Coast and East Coast will see the broadcast, while significant portions of the Midwest, Florida and the South will see the game, too.

49ers vs. Browns live stream

For fans who are unable to watch the television broadcast, fuboTV offers a free seven-day trial for first-time users.

Additionally, fans can stream by going to foxsports.com or downloading the official Fox Sports app. In-market fans can go to 49ers.com or download the official 49ers app (Bay Area) or Browns app (greater Cleveland area).

NFL+ subscribers can watch the replay in full once the game has concluded.