49ers Playoff Game Saturday: 49ers vs. Seahawks spread, over/under, how to watch, prediction, history

(Photo by Kyle Terada-USA TODAY Sports)
(Photo by Kyle Terada-USA TODAY Sports) /

The San Francisco 49ers will begin their 2022 playoff journey when they host the Seattle Seahawks on Saturday to kick off Super Wild Card Weekend.

Before the San Francisco 49ers can get closer to winning their sixth Super Bowl in franchise history, they’ll have to first defeat the Seattle Seahawks on Saturday in the opening round of the 2022 playoffs as part of Super Wild Card Weekend.

San Francisco 49ers vs. Seattle Seahawks Odds, Spread, Over/Under & Prediction for Super Wild Card Weekend

Odds courtesy of FanDuel

Point Spread:

  • 49ers -9.5 (-110)
  • Seahawks +9.5 (-110)


  • 49ers -500
  • Seahawks +385


  • 42 points
    • Over -110
    • Under -110


The 49ers being favored by more than a touchdown in their home building seems like a pretty good indication that they will defeat the Seahawks on Saturday.

San Francisco is favored by 9.5 points this weekend, and in home games where oddsmakers have the 49ers favored by nine points or more, they haven’t lost a contest since Week 15 of the 2019 season. During the playoffs, San Francisco hasn’t lost a home matchup in which oddsmakers had them favored to win by seven points or more since 1996.

With the 49ers winning both of their regular-season games against the Seahawks in 2022, we should expect a similar outcome to take place inside Levi’s Stadium on Saturday.

Prediction: 49ers win

How to watch San Francisco 49ers vs. Seattle Seahawks on Super Wild Card Weekend

Saturday’s NFC Wild Card matchup between the 49ers and Seahawks will air nationally on FOX at 1:30 p.m. pacific time, with Joe Davis and Daryl Johnston calling all the action from inside the broadcast booth.

How to stream San Francisco 49ers vs. Seattle Seahawks on Super Wild Card Weekend

For those who would like to stream this weekend’s meeting between two NFC West rivals, check out fuboTV. The streaming service offers Cloud DVR, local channels in most markets, no cancellation fees, and for new users, they are currently offering a free trial for seven days.

Some other streaming options that could be broadcasting Saturday’s game, depending on your location, include the following.

  • DirecTV Stream
  • NFL Sunday Ticket
  • Hulu + Live TV
  • Sling TV
  • YouTubeTV
  • NFL+ (mobile only)

How to listen to San Francisco 49ers vs. Seattle Seahawks on Super Wild Card Weekend

For fans who would like to listen to the radio broadcast of Saturday’s postseason contest, Northern California’s KNBR 680 and KSAN 107.7 The Bone will have the contest on their stations, with Greg Papa and Tim Ryan calling the action from the booth.

Steve Raible and Dave Wyman are on the call for the Seahawks radio feed, which will be broadcast on Seattle’s 710 KIRO-AM and 97.3 KIRO-FM.

San Francisco 49ers vs. Seattle Seahawks History

All-Time Head-to-Head Record:

  • Seahawks lead the all-time series 30-19

Last Meeting:

San Francisco 49ers next game and schedule

If the 49ers are able to get a win on Saturday, their playoff journey will continue next week in the NFC Divisional round. Depending on how the upcoming weekend goes, San Francisco’s second playoff game could come against the Minnesota Vikings, Dallas Cowboys, or Tampa Bay Buccaneers.

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(Game odds refresh periodically and are subject to change.)