49ers Game Sunday: 49ers vs. Cardinals injury report, spread, over/under, how to watch, prediction, history

With a slim chance to still end up as the No. 1 seed in the NFC, the San Francisco 49ers will be looking to get a Week 18 win over the Arizona Cardinals.

In their final game of the 2022 regular season, the San Francisco 49ers will host the underwhelming Arizona Cardinals for a Week 18 matchup inside Levi’s Stadium.

San Francisco 49ers injury report vs. Arizona Cardinals in Week 18

49ers

• Aaron Banks (OG) – OUT with ankle and knee injuries
• Jimmy Garoppolo (QB) – OUT with a foot injury
• Kevin Givens (DT) – OUT with a knee injury
• Dre Greenlaw (OLB) – OUT with a back injury
• Ambry Thomas (CB) – OUT with an ankle injury
• Arik Armstead (DT) – QUESTIONABLE with foot and ankle injuries
• Javon Kinlaw (DT) – QUESTIONABLE with a knee injury

Cardinals

• Zach Allen (DE) – OUT with a hand injury
• Robbie Anderson (WR) – OUT with a back injury
• Zaven Collins (LB) – OUT with a calf injury
• James Conner (RB) – OUT with knee and shin injuries
• Antonio Hamilton (CB) – OUT with a hip injury
• DeAndre Hopkins (WR) – OUT with a knee injury
• Colt McCoy (QB) – OUT with a concussion
• Marco Wilson (CB) – OUT with a neck injury
• Victor Dimukeje (LB) – QUESTIONABLE with an illness
• Leki Fotu (DL) – QUESTIONABLE with a shoulder injury
• Josh Jackson (CB) – QUESTIONABLE with a hamstring injury
• Tanner Vallejo (LB) – QUESTIONABLE with knee and wrist injuries

San Francisco 49ers vs. Arizona Cardinals Odds, Spread, Over/Under & Prediction for Week 18

Odds courtesy of FanDuel

Point Spread:

• 49ers -14 (-110)
• Cardinals +14 (-110)

Moneyline:

• 49ers -950
• Cardinals +640

Over/Under:

• 39.5 points
  • Over -110
  • Under -110

Prediction:

It has been more than 25 years (Week 10 of the 1995 season) since the 49ers last lost a game in which they were favored by oddsmakers to defeat their opponent by 14 points or more.

With the Cardinals heading into the matchup with an unimpressive 4-12 record and just one win in their last nine games, we should expect San Francisco to earn their 13th win of the 2022 season on Sunday.

Prediction: 49ers win

How to watch San Francisco 49ers vs. Arizona Cardinals in Week 18

Sunday’s NFC West matchup between the 49ers and Cardinals will air on FOX at 1:25 p.m. pacific time, with Chris Myers and Robert Smith calling all the action from inside the broadcast booth.

The image below from 506sports.com shows where Sunday’s matchup will be airing locally around the country.

How to stream San Francisco 49ers vs. Arizona Cardinals in Week 18

For those who would like to stream for this weekend’s regular-season finale, check out fuboTV. The streaming service offers Cloud DVR, local channels in most markets, no cancellation fees, and for new users, they are currently offering a free trial for seven days.

Some other streaming options that could be broadcasting Sunday’s game, depending on your location, include the following.

• DirecTV Stream
• NFL Sunday Ticket
• Hulu + Live TV
• Sling TV
• YouTubeTV
• NFL+ (mobile only)

How to listen to San Francisco 49ers vs. Arizona Cardinals in Week 18

For fans who would like to listen to the radio broadcast of this Sunday’s matchup taking place inside Levi’s Stadium, Northern California’s KNBR 680 and KSAN 107.7 The Bone will have the contest on their stations, with Greg Papa and Tim Ryan calling the action from the booth.

Dave Pasch and Ron Wolfley are on the call for the Cardinals radio feed, which will be broadcast on Arizona’s KMVP‑FM 98.7.

San Francisco 49ers vs. Arizona Cardinals History

All-Time Head-to-Head Record:

• 49ers lead the all-time series 33-29

Last Meeting:

• San Francisco defeated Arizona 38-10 in Week 11 of the 2022 season.

San Francisco 49ers next game and schedule

Following their regular-season finale against the Cardinals on Sunday, the 49ers’ next matchup will take place in the playoffs. San Francisco still has a chance at finishing as the No. 1 seed in the NFC, so it’s actually possible that they could end up with a bye in the first round of the playoffs.

If the 49ers don’t finish as the NFC’s No. 1 seed, then their first postseason contest will happen next weekend, with Saturday, January 14th being the earliest possible date for their opening-round matchup to take place.

(Game odds refresh periodically and are subject to change.)