49ers game today vs. Commanders: Injury report, spread, over/under, schedule, live stream, TV channel

The 49ers host the Commanders on a Christmas Eve special, and Niner Noise breaks down the latest injury news, betting odds and how you can watch live.

One of two things could go terribly wrong for the San Francisco 49ers during their Week 16 home game against the playoff-desperate Washington Commanders.

The Niners would have to play sloppy enough to allow Washington to hang around in the game, particularly knowing the Commanders boast a bottom-of-the-league offense that has struggled to score at least 20 points in a game all season long. While both teams boast a strong defense, San Francisco’s top-ranked defense still holds the edge here, too, meaning it’ll take mistakes from the 49ers’ vantage point to allow Washington to win.

And then, of course, are the injuries.

The Niners don’t seem to treat this as a throwaway game, meaning starters will play if they’re healthy.

Speaking of that injury report, though, let’s start there in our preview piece for this Week 16 bout.

49ers injury report vs. Commanders Week 16

San Francisco is still keeping quarterback Jimmy Garoppolo and wide receiver Deebo Samuel on the active roster despite injuries, and Samuel could potentially return in a week or two anyway.

However, the following players appeared on the 49ers’ Week 16 injury report:

• QB Jimmy Garoppolo (foot): OUT
• DL Kevin Givens (knee): OUT
• WR Deebo Samuel (ankle, knee): OUT
• RB Jordan Mason (hamstring): Questionable
• CB Charvarius Ward (concussion): Questionable
• DB Tarvarius Moore (knee): Questionable
• DL Kerry Hyder (ankle): Questionable
• CB Ambry Thomas (ankle): Questionable

Already having placed defensive tackle Hassan Ridgeway (pectoral) on injured reserve, the Niners’ defensive line could be awfully thin if Hyder is unable to play and with Givens already out.

49ers vs. Commanders odds, spread, over/under and betting pick, Week 16

The spread has been moving back in Washington’s favor ever since the oddsmakers at WynnBET opened up with San Francisco as a 7.5-point home favorite.

That said, the 49ers are still 6.5-point favorites in this one, and their moneyline is -350. The Commanders’ moneyline, meanwhile, is +250.

The over/under for the game is 37.5.

Let’s be simple about this one. The Niners are coming off a mini bye week after having beaten the Seattle Seahawks on Thursday Night Football in Week 15, while an offensively challenged Washington squad has to travel across the country on a short week.

Advantage: San Francisco, and it’ll improve to 11-4 with a 24-13 victory in our prediction.

Game odds refresh periodically and are subject to change.

What TV channel is the 49ers game on Week 16?

CBS will broadcast Saturday’s bout between the 49ers and Commanders, which will kick off on Dec. 24 at 4:05 p.m. ET from Levi’s Stadium in Santa Clara, California.

The entire West Coast, including parts of Nevada, Idaho and Montana, will be able to view the game, and other portions of the Midwest and the greater Washington D.C. area will, too.

Related Story: Experts are picking 49ers to easily defeat Commanders in Week 16

Kevin Harlan will be on play-by-play duties with Trent Green doing color commentary. Melanie Collins will be on the sidelines.

49ers vs. Commanders live stream

Fans who are unable to watch Saturday’s game on television can stream the game to preferred devices by signing up with fuboTV, which offers a free seven-day trial for first-time users.

Additionally, in-market fans can go to 49ers.com or download the official 49ers app to stream the game.

49ers next game and schedule

The Niners have their final road game of the regular season after hosting Washington, and they’ll travel out to Las Vegas for a New Year’s Day showdown with their former Bay Area rivals, the Raiders.

After that, it’s home for San Francisco against the Arizona Cardinals before the Wild Card round of the NFL playoffs begins.

• Week 17 @ Las Vegas Raiders: Sunday, Jan. 1 at 4:05 p.m. ET
• Week 18 vs. Arizona Cardinals: TBD