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49ers schedule release: Predicting outcome of each game in 2022

Robert Morrison
Robert Morrison

Niner Noise

Aug 29, 2021; Santa Clara, California, USA; San Francisco 49ers quarterback Trey Lance (5) runs the ball against the Las Vegas Raiders in the second quarter at Levi's Stadium. Mandatory Credit: Cary Edmondson-USA TODAY Sports

With the 49ers 2022 schedule now available, Niner Noise attempts to predict what games they’ll win, which ones they’ll lose, and why.

The NFL regular-season schedule was released on Thursday, May 12 in primetime, allowing fans of the 49ers an opportunity to see when the Niners’ games will take place during the 2022 regular season.

While the opponents and home/away designations have been set since the close of the 2021 season, the “when” was the final question on the docket for the NFL schedule makers, a query that was answered on Thursday night.

Despite ending their season in the NFC Championship game, the 49ers benefit from a third-place schedule, having finished behind both the Los Angeles Rams and Arizona Cardinals in the NFC West. So while the Rams and Cardinals will both have a more difficult schedule based solely on the 2021 winning percentage of their 2022 opponents, the Niners get a slight reprieve, landing tied for fifth according to that metric.

There are plenty of questions left to answer about the 2022 49ers, mostly swirling around the quarterback position and whether second-year signal-caller Trey Lance is going to be the starter heading into the season (likely), and what will happen to incumbent starter Jimmy Garoppolo (your guess is as good as mine).

For the purpose of this exercise, the assumption is that Lance will be the starter and that there will be little change to the expected roster that the Niners will field at the close of the preseason.

With all that established, let’s dive into the 49ers’ 2022 schedule and see how things might shake out for the Niners.

Oct 31, 2021; Chicago, Illinois, USA; San Francisco 49ers running back Eli Mitchell (25) Mandatory Credit: Mike Dinovo-USA TODAY Sports
Oct 31, 2021; Chicago, Illinois, USA; San Francisco 49ers running back Eli Mitchell (25) Mandatory Credit: Mike Dinovo-USA TODAY Sports

Week 1

Sunday, September 11 at Chicago Bears, 1 PM ET/10 AM PT

Poor Justin Fields.

Not only did he lose a lot of games in his rookie season (the Bears were 2-8 in games he started), but he was often running for his life beyond a bad offensive line trying to throw to one of the NFL’s worst receiving units.

And all the Bears did was let his best option (Allen Robinson) get away in free agency and drafting just two offensive skill players in the 2022 NFL Draft: Tennessee wide receiver Velus Jones in the third round and Baylor running back Trestan Ebner in round six.

To their credit, the Chicago front office did recognize the weakness of their offensive line, so they used four of their eleven picks on players to project Fields, albeit none until the fifth round.

From the outside looking in, the Bears appear to realize this is a long-term rebuild, having traded away Khalil Mack and stockpiling young players, but one thing is for certain: that is going to make year 2 for Justin Fields difficult as well. Mostly due to the fact that his skill position players are highlighted by guys like wide receivers  Darnell Mooney and Byron Pringle, running back David Montgomery, and tight end Cole Kmet, all of whom would likely be no.2 or worse options on better teams.

It’s going to be another long year in Chicago for Bears fans.

All that said, the Bears should be a soft landing spot for Trey Lance’s first NFL Week 1 start, and the defense, provided it can tackle Fields, should be able to keep the Bears under wraps.

Prediction: 49ers win big

Record: 1-0

Week 2

Sunday, September 18 vs Seattle Seahawks, 4:05 PM ET/1:05 PM PT

The home opener comes against an old nemesis, albeit a weakened one. And it makes for an easier start to 2022 for the 49ers.

Seattle is not going to be very good in 2022.

They weren’t all that good in 2021, although the 49ers did manage to find a way to lose to them twice last year, a telling statement about how division games can be the ultimate equalizer if there ever was one.

But the fact of the matter is that those wins came largely on the shoulder of one man who seemed to be a perpetual thorn in the 49ers’ side: now Broncos’ quarterback Russell Wilson, whom the Seahawks traded for a load of picks and players this offseason.

And so that means Pete Carroll will be riding a duo of quarterbacks that are at best seen as reclamation projects in Drew Lock and Geno Smith and a continued eye toward building the running game, as evidenced by their finally investing in an offensive lineman now that Wilson is in Denver. Neither strategy should rile up much fear in the hearts of NFL opponents, least of all the 49ers, who should be trotting out a defense that will be among the league’s best in 2022.

All that to say: it’s time for the 49ers to exorcise some demons of years past and really put a hurting on the Seahawks this season. If Seattle’s goal is to be as bad as possible for 2022, there’s no reason the 49ers should oblige them in that aim.

For the home opener, this is one of the more favorable matchups the 49ers could have gotten and it should make for a nice beginning to the regular season.

Prediction: 49ers win, annoyingly closer than it should be

Record: 2-0

Week 3

Sunday, September 25 at Denver Broncos, 8:20 PM ET/5:20 pm PT

Just when 49ers fans thought they were getting rid of Russell Wilson, the Seahawks went and traded him to a team the Niners get to visit in 2022.

To be sure, Wilson is now in a much better situation than he’s been in over the last couple of years in Seattle, a team that leaned heavily on its former quarterback to pull magic out of the air to win games.

The same will not be said for the Broncos, who have a solid group of skill position players for Wilson to work with such as wide receivers Courtland Sutton and Jerry Jeudy and running back Melvin Gordon, although losing tight end Noah Fant in the Wilson trade will sting a little.

Denver also boasts one of the NFL’s better defensive units, led by cornerbacks Ronald Darby and Patrick Surtain II, EDGE rushers Bradley Chubb and Randy Gregory, and safety Justin Simmons, not to mention former 49ers K’Waun Williams and DJ Jones.

The Broncos, like the rest of the AFC West, are coming for the Chiefs, something the Wilson trade makes abundantly clear, but the question will be whether the quarterback will adjust to a new circumstance or whether his small dropoff in 2021 was a sign of things to come or an indication of how poor his situation was in Seattle.

Having the 49ers come to Denver will be a boon for the Broncos, as the riotous crowd and the thin air can do a number on the opposition. But it being early in the season means both teams will still be finding their footing, especially Wilson and his new team.

Prediction: 49ers win a close one

Record: 3-0

Week 4

Monday, October 3 vs Los Angeles Rams, 8:15 PM ET/5:15 PM PT

The defending Super Bowl champs do not appear to be appreciably better in 2022, having lost key players such as wide receiver Odell Beckham, linebacker/EDGE rusher Von Miller, and offensive tackle Andrew Whitworth this offseason, all vital pieces to their run to the championship last season.

And, to be frank, the 49ers, in spite of losing to the Rams in the NFC Championship game, have still won six of the last seven over the Rams and were up 17-7 heading into the 4th quarter of the lone loss before falling apart in the final minutes of that contest and losing the right to go to the Super Bowl.

Kyle Shanahan is 7-4 against his old coaching buddy Sean McVay and that has to count for something, even though 49ers fans would gladly trade that season-ending victory in 2017 with Sean Mannion at the helm for the Rams for their win streak to be still intact.

Oh well. It’s another season and saying that momentum carries over in situations like this is obviously lazy analysis. The key question will be how the change in quarterback for the 49ers will impact this matchup, a statement that really is one that could cover the entirety of their season.

Given the start to the season, the 49ers will have, they should have had the right combination of easier teams to get them rolling and a stronger test in Week 3 to put them in a position to get off to a hot start. This game could go either way, as it’s two strong teams, but I’ll give it to the home team.

Prediction: 49ers win a close one

Record: 4-0

October 27, 2019; Santa Clara, CA, USA; San Francisco 49ers tight end George Kittle (85) Mandatory Credit: Kyle Terada-USA TODAY Sports
October 27, 2019; Santa Clara, CA, USA; San Francisco 49ers tight end George Kittle (85) Mandatory Credit: Kyle Terada-USA TODAY Sports

Week 5

Sunday, October 9 at Carolina Panthers, 4:00 PM ET/ 1:05 PM PT

The Panthers are an NFL team stuck in purgatory.

Carolina has some interesting pieces, especially on defense, with players like cornerbacks Jaycee Horn and CJ Henderson, EDGE rusher Brain Burns, and safety Jeremy Chinn. There are even things to like about their offense, including running back Christian McCaffery (even if he can’t stay on the field) alongside wideouts Robbie Anderson and DJ Moore.

And yet, there remains the quarterback issue, one that is one of the direr in the league.

Sam Darnold is set to return, probably as the odds-on favorite to start Week 1, but he was largely ineffective in 12 games last season, throwing for just over 2500 yards and completing under 60% of his passes. His $18.5 million cap hit due to the 5th year option the Panthers picked up before he played a snap for them means he’s on the team one way or another.

Behind him are PJ Walker, who filled in for Darnold for five games last season but wasn’t any better for the Panthers, and two rookies – 2022 third-round pick Matt Corral out of Ole Miss and Davis Cheek, an undrafted free agent out of Elon – neither of which will inspire much hope for the 2022 season, even if Corral might have promise down the road.

And then of course there’s the Jimmy Garoppolo question, as the Panthers remain a team who could be in play for the 49ers’ quarterback. The conundrum there would be surrounding Darnold, who would be set to be raking in his massive salary while likely sitting on the bench, and the need for Carolina to retain three signal-callers in order to keep Corral around.

This is all topped off by the fact that head coach Matt Rhule is on maybe the NFL’s hottest hot seat and needs to win now in a division currently owned by Tom Brady and the Bucs. It’ll be a miracle if the Panthers aren’t at or near the cellar of this division.

All this to say: if the 49ers don’t win this, particularly with the benefit of it not being a 10 AM PT time game, it’s bad news.

Prediction: 49ers win big

Record: 5-0

Week 6

Sunday, October 16 at Atlanta Falcons, 1:00 PM ET/10:00 AM PT

If there is a saving grace for the Carolina Panthers, it’s that the Atlanta Falcons also play in their division and they seem to be going about the plan at quarterback in a similar manner.

Atlanta shipped longtime starter, Matt Ryan, to the Colts this offseason and opted to bring in Marcus Mariota as a short-term bridge option while drafting former Cincinnatti QB Desmond Ridder in the third round of the 2022 NFL Draft to be their quarterback of the future.

On paper, it looks a lot smarter than what the Panthers are doing, since Mariota’s contract will either work as a backup contract in either year if Ridder wins the job this year or can be moved on from with massive cap savings next year if the former Titan proves a surplus to requirements in 2023.

The rest of the roster is pretty bleak, however, in spite of a few bright spots. Those include their last two first-round draft picks, former Florida tight end Kyle Pitts and USC wideout Drake London. Outside of that, skill players are especially thin on offense, even if Cordarrell Patterson is back after a breakout season in 2021.

Their defense, which was among the worst in the NFL last season, doesn’t stand to look much better, although cornerback AJ Terrell, defensive tackle Grady Jarrett, and linebacker Deion Jones are still here.

The fight for the bottom of the NFC South will be between Atlanta and Carolina, and it’s fortunate the 49ers get to see them both in 2022.

In spite of the long east coast road trip, the 49ers should be able to stay nearby and set themselves up for yet another win to start the season.

Prediction: 49ers win big

Record: 6-0

Week 7

Sunday, October 23 vs Kansas City Chiefs, 4:25 PM ET/1:25 PM PT

To be clear, the Chiefs are still among the AFC’s elite teams and are among the favorites to represent their conference in the Super Bowl and win a second championship within five years.

But that doesn’t mean they’ve not seen a noticeable deprecation in the quality of their team since last season. The departures of players like wideout Tyreek Hill and safety Tyrann Mathieu will hurt them, especially when you consider that Hill’s replacements are JuJu Smith-Schuster and Marquez Valdes-Scantling, two good but not great pass-catching options.

They still have All-Pro tight end Travis Kelce, of course, oh, and some quarterback named Mahomes. That alone will be enough to make them contenders.

The 49ers benefit from the Chiefs having to come to Santa Clara for this one, a place that Kansas City has played in just one time, a 2014 contest that was notable as Alex Smith’s return to play the 49ers, a game he lost to Colin Kaepernick and the Niners 22-17 early in that season.

Still, all good things must come to an end, and after a long stretch of games (and wins), this could be the first major stumble of the 49ers’ season, albeit to a very good team.

Prediction: Chiefs win a close one

Record: 6-1

Week 8

Sunday, October 30 at Los Angeles Rams, 4:25 PM ET/1:25 PM PT

The 49ers, surprisingly, get their division foes out of the way before the bye week, leaving two games against the Cardinals and one against the Seahawks to complete their NFC West schedule.

Having already predicted a win for the 49ers at Levi’s Stadium in Week 4 on Monday Night Football, I could see this one, as with the first game, going either way.

For now, it’s best to predict yet another close and exciting game, although this one going the other direction than the first matchup did.

Still, a 6-2 record heading into the Week 9 bye is not a bad way to get rolling.

Prediction: Rams win a close one

Record: 6-2

Week 9

BYE WEEK

Deebo Samuel, San Francisco 49ers
Oct 10, 2021; Glendale, Arizona, USA; San Francisco 49ers wide receiver Deebo Samuel (19) Mandatory Credit: Michael Chow-USA TODAY Sports

Week 10

Sunday, November 13 vs Los Angeles Chargers, 8:20 PM ET/5:20 PM PT

This is not a fun year to draw the AFC West as your opposite number. While the Chiefs have controlled the division for the last several years, each of the other teams in the group has clearly set their sights on going after Kansas City.

None seem more poised to possibly unseat Mahomes and the Chiefs than the Chargers and third-year quarterback Justin Herbert, who has already had two solid NFL seasons and is looking to make the leap into the stratosphere of elite quarterbacks.

The Chargers missed out on the playoffs last season due to a late-game coaching mistake in their final game against the Raiders, yes, but also because their defense didn’t live up to expectations set by their offense, a sad statement since head coach Brandon Staley was a defensive coordinator before taking the Chargers’ gig.

While their offense was a top-5 unit in terms of scoring, yards, and passing, the defense was near the bottom of the league in those categories and was especially bad in stopping the run. Their offense managed to put up 474 points in 17 games. The defense gave up 459 points. Not exactly a recipe for success.

So they added to a defense that already featured EDGE rusher Joey Bosa and safety Derwin James, trading for EDGE rusher Khalil Mack from Chicago and signing former Patriots’ cornerback JC Jackson, one of the most sought-after players in this offseason’s free agency class.

The retool that began with the drafting of Herbert seems to be complete. Now it’s time for the Chargers to see if they can take the next step and truly contend for a title.

The timing of this game, however, really works out well for the 49ers. They play in Los Angeles, a short trip, in Week 8 on Sunday afternoon followed by their bye week, and then don’t have to worry about the Chargers until Sunday Night Football in Week 10.

This should give Kyle Shanahan and his staff plenty of time to game plan for Herbert and the Chargers. And while the SNF matchup means we’ll get a lot of talk about the Bosa Brothers, it should also make for must-see-TV and a game I think the 49ers can win, even if it’s a close one.

Prediction: 49ers win a close one

Record: 7-2

Week 11

Monday, November 21, at Arizona Cardinals (in Mexico City), 8:15 ET/5:15 PT

The Cardinals had a bizarre 2021 season, jumping out to a 9-2 start before, as they’ve done pretty much like clockwork for each of the last few years, collapsing in the season’s final stretch after their bye week.

Arizona finished 11-6, good enough for second in the highly touted NFC West, but were annihilated, 34-11, by their division foes and eventual Super Bowl champions Los Angeles Rams in the Wild Card game.

Add yet another late season underperformance to a turbulent offseason that featured an often disgruntled quarterback in Kyler Murray and the six-game suspension of wide receiver DeAndre Hopkins and you’ve got the makings of what could be a rough 2022 for the team from the desert.

Of course, the 49ers will not miss out on Hopkins, with this Week 11 contest coming well after the wideout’s suspension will have been served.

The 49ers should be eyeing a reversal of fortunes from the last few seasons over the Cardinals, a team the Niners have lost to seven out of ten times since Kyle Shanahan took over as head coach in 2017, including sweeps in 2017, 2018, and 2021.

As constructed, and given the tumult in the building, the 49ers should be able to grab a victory.

The Monday Night Football contest in November will take place in Mexico City, and while the Cardinals will technically be the home team for the contest, 49ers fans travel well, as evidenced most recently by the playoff games against Dallas and Green Bay last season, as well as multiple trips to LA’s SoFi Stadium since it opened. So expect it to be a very pro-49ers crowd.

Prediction: 49ers win in a classic NFC West clash

Record: 8-2

Week 12

Sunday, November 27 vs New Orleans Saints, 4:25 PM ET/1:25 PM PT

For some reason, when ESPN’s Dan Orlovsky ranked his top five teams in the NFC on May 2, he included both the Philadelphia Eagles (at no.5) and the New Orleans Saints (at no.3).

Respectfully: this makes no sense.

The Saints will be a feisty team in the NFC this year, maybe, because they just don’t have the offensive firepower they’ve had in recent years with Drew Brees at quarterback.

Speaking of quarterbacks, the Saints are a pretty clear example of a team that has a lot of quarterbacks but doesn’t really have one that stands out as the guy who can take this team to the next level.

Ostensibly, Jameis Winston is back to be the starter, but he’s coming off a major injury and has a history of being spectacular while also giving the ball away at record levels. Taysom Hill is still there, but any misgivings the organization has had about his ability as an actual quarterback should have shipped out when former head coach Sean Payton did. They signed Andy Dalton to a free agent contract that includes a $3 million cap hit that becomes dead money if he’s cut. And all the while they still have former Notre Dame signal-caller Ian Book, who played (poorly) in a loss to the Dolphins in Week 16 last year.

On top of all that, the question marks remain about their skill position players outside of wide receiver Michael Thomas, who has played in seven games over the last two seasons, all of which came in 2020, and running back Alvin Kamara, who continues to show why giving massive contracts to running backs is a dangerous game (and still has pending legal trouble from an issue in Las Vegas after the Pro Bowl).

So again, respectfully: how is this team among the NFC’s elite?

This is a team the 49ers should be able to beat, especially since it’s a home game.

Prediction: 49ers win

Record: 9-2

Week 13

Sunday, December 4 vs Miami Dolphins, 4:05 PM ET/1:05 PM PT

The Dolphins certainly have the look of a team that wants to push for contention in not just the AFC East but the AFC at large, although that last part will be difficult given how deep the AFC is coming into this season.

They began by bringing in former 49ers’ offensive coordinator Mike McDaniel to be their head coach, hoping he’ll bring with him a version of the Shanahan offense that has become a staple in many offensive schemes in the NFL. Miami followed that up by trading for Tyreek Hill and signing him to a massive extension, as well as bringing in guys McDaniel has familiarity with such as running back Raheem Mostert and wide receiver Trent Sherfield.

The transactions look like a team trying to build its offense to look like the 49ers have over the last few seasons, including signing a fullback in Alec Ingold.

But the elephant in the room remains: will quarterback Tua Tagovailoa be able to stay on the field and, if he does so, can he be efficient enough with all his new toys on offense, which already included wide receiver Jaylen Waddle and tight end Mike Gesicki.

If Tua is average at best, the Dolphins will be a good team. If he struggles, then newly signed Teddy Bridgewater will be waiting in the wings to step in and do what Tagovailoa can’t.

This is the second of three straight home games for the 49ers and while the Dolphins look to be a team primed to make some noise, the quarterback question is one that is far too up in the air.

Prediction: 49ers win a good game

Record: 10-2

George Kittle, San Francisco 49ers
Dec 5, 2021; Seattle, Washington, USA; San Francisco 49ers tight end George Kittle (85) Mandatory Credit: Joe Nicholson-USA TODAY Sports

Week 14

Sunday, December 11 vs Tampa Bay Buccaneers, 4:25 PM ET/1:25 PM PT

Tom Brady, like time, marches on.

After a short-lived retirement, followed by rumors that he would only return if the Bucs traded him to San Francisco, Brady ultimately chose to return for his 23rd NFL season and third in Tampa. He’ll be 45 in August.

The team around him has lost some pieces, but retains wide receivers Mike Evans and Chris Godwin (although the latter is coming off a major injury), running back Leonard Fournette, and tight end Cameron Brate (although Rob Gronkowski has yet to decide on a return).

The defense remains stout as well, with defensive tackle Vita Vea, linebacker Devin White, EDGE rusher Shaq Barrett, safety Antoine Winfield Jr, and cornerback Carlton Davis among its standouts.

Conversations have been happening around Brady’s sudden dropoff for years now, but at this point, he seems to have quieted the critics. Seeing as there’s no point of comparison at this juncture, that makes a ton of sense.

The Bucs remain a good team, and with Brady at the helm, they’ll be a tough one to beat. And I think this is where the 49ers’ second win streak of 2022 comes to an end. At the hands of lifelong 49ers fan Tom Brady.

Prediction: Bucs win a good matchup

Record: 10-3

Week 15

Thursday, December 15 at Seattle Seahawks, 8:15 PM ET/5:15 PM PT

Much like Seattle made for a nice home opener, they also serve as a reasonable opponent for the 49ers to have to worry about on a short week.

Obviously, the Seahawks are a division foe and so the 49ers’ staff is familiar with them and what their head coach Pete Carroll wants to do.

But, as previously noted, the 2022 version of the Seattle Seahawks doesn’t figure to be a good team and so they can provide the Niners with a chance to get right after a tough loss to the Bucs in Week 14.

Prediction: 49ers win, hopefully, this time in an easier fashion

Record: 11-3

Week 16

Saturday, December 24 vs Washington Commanders, 4:05 PM ET/1:05 PM PT

The newly dubbed Commanders actually have the makings of a decent football team.

They’ve got weapons on offense, including wideouts Terry McLarin and Curtis Samuel and running back Antonio Gibson, to go along with a formidable defensive line that includes former no.1 overall draft pick EDGE rusher Chase Young, defensive tackles Daron Payne and Jonathan Allen, and depth pieces like EDGE rusher Montez Sweat.

But the Commanders, like most of the teams in the NFL, will only go so far as their new quarterback will take them. And that quarterback, Carson Wentz, is one of the league’s more unpredictable.

Wentz has never really recovered his MVP-level play from his injury-shortened 2017 season, one that saw his backup, Nick Foles, win the Eagles their first Super Bowl, and seems to have sent the former North Dakota State Bison into a spiral of erratic play.

The 49ers have seen that he’s still capable of spectacular play (this will be the third year in the row that Wentz has faced the 49ers at Levi’s Stadium, having beaten them as an Eagle on Sunday Night Football against Nick Mullens and the Niners in 2020 and then again on SNF last year as the Colts’ QB in one of the seasons’ uglier games).

But Wentz also tanked the Colts’ playoff hopes last season with particularly poor play down the stretch, leading to Indianapolis not only missing the tournament altogether but to their making the decision to trade him to Washington.

This game comes with another scheduling quirk for the 49ers. They’re coming off a Thursday Night Football game in Week 15 and instead of getting to wait until the Sunday of Week 16, they have to play an afternoon game on Saturday instead.

Still, I don’t think that should matter, as by this point, you have to think the 49ers will have firmly established themselves as contenders in the NFC.

Prediction: 49ers win, although Wentz keeps it closer than you’d hope

Record: 12-3

Week 17

Sunday, January 1 at Las Vegas Raiders, 4:05 PM ET/1:05 PM PT

The Raiders got better this offseason.

The Raiders still might be the worst team in the AFC West.

Both things are true, mostly because the division is loaded and Las Vegas may possess a solid, but still division-worst quarterback situation.

It’s easy to forget the Raiders made the playoffs last year, pulling themselves out of a 6-7 hole after a Week 14 loss to Kansas City to win four straight and sneak into the final Wild Card slot. They lost to the eventual AFC champion Cincinnati Bengals, but the resiliency the team showed after the midseason firing of former head coach John Gruden was admirable.

This doesn’t mean they won’t finish last in a highly competitive division, mostly because somebody has to.

In 2021, the Raiders were middle of the road on both offense and defense, although they passed the ball much better than they ran it while stopping the run slightly better than they stopped the pass. It was a weird year in Vegas to be sure.

They attempted to improve on defense by bringing in former Cardinals EDGE rusher Chandler Jones, adding cornerback depth in form of Anthony Averett and Darius Phillips, and inking EDGE rusher Maxx Crosby to a multi-year extension. But the pass-receiving talent in their own division will put this unit to the test.

Offensively, the big move was to trade for former Packer Davante Adams, reuniting him with quarterback Derek Carr, who was his signal-caller in college at Fresno State. After that, the key receiving targets will be slot receiver Hunter Renfrow and tight end Darren Waller, two of the better players at their respective positions in the NFL.

The offense will likely be able to do enough, but the Raiders can’t continue to yield more points than they score (they had a -65 point differential in 2021, the worst of any playoff team) if they want to compete in their loaded division, let alone sniff the playoffs again this season.

This particular game renews an old rivalry, albeit in a new location, as it’s the 49ers’ first trip to Las Vegas to take on the Raiders in their new home. Past matchups, even in the preseason, have gotten heated, resulting in violence that led to the organizations ending their annual preseason game.

Let’s hope for a good game, one that could matter a great deal to both teams, as this late-season matchup could have an impact on the playoffs in both conferences.

Prediction: 49ers win a good one

Record: 13-3

Week 18

vs. Arizona Cardinals,  Time and Date TBD

It is a little surprising to see the Cardinals as the final game of the season, especially since the last couple of years the NFL has shown who it expects to be in contention for the NFC West division title with this final game.

The Cardinals don’t feel like the team who might be up there with the 49ers, but here we are, looking at a TBD for both the date and time for the 49ers’ Week 18 game against a division foe.

Sure, it could end up with this game sliding into a Sunday afternoon slot if it doesn’t have any major playoff implications. But it could also just as easily be another primetime game for the 49ers if it ends up serving as the de facto NFC West Championship game (although that feels unlikely at this point).

This game’s outcome depends on what each team needs out of it, but no matter what, I fully expect the Cardinals to be a team the 49ers can beat twice. For now, let’s call the split.

Prediction: Cardinals by an inch

Record: 13-4

It shouldn’t need to be said, but the assumption of these predictions hinges on one very important element: how well Trey Lance acclimates to being the undisputed quarterback for the San Francisco 49ers.

He doesn’t have to perfect, because the other elements of the 49ers roster are strong enough to support Lance as he grows into his new role. And for that reason, the expectations are high for the 2022 Niners.

Robert Morrison

Robert Morrison

Robert Morrison is a husband, father, educator, writer, and musician currently based in Rock Hill, SC. He's a lifelong 49ers fan who likes to find the big picture of what's happening around the team and tell the stories he sees that matter.