49ers game Sunday: 49ers vs. Eagles odds and prediction for NFL Week 2 game
By Peter Panacy
The 49ers look to go a perfect 2-0 on the road to start the season, but that’ll mean pulling off another win against a 1-0 Eagles squad in Week 2.
It wasn’t always pretty, but the San Francisco 49ers managed to stave off a disaster in Week 1 and held onto a late surge by the Detroit Lions en route to pulling off a 41-33 victory to kick off the 2021 regular-season campaign.
The win hurt, though, especially with the realization the Niners lost cornerback Jason Verrett to what’s appearing to be a season-ending ACL tear.
And while that highlighted the major concerns head coach Kyle Shanahan may face in coming weeks, the next task will be to face off on the road again, this time against the 1-0 Philadelphia Eagles, who just routed the Atlanta Falcons 32-6.
49ers vs. Eagles odds Week 2
According to the oddsmakers at WynnBET, San Francisco enters this Week 2 bout as a 3.5-point favorite over Philly despite being on the road again.
The 49ers’ moneyline is -190, while the Eagles are the underdog for this contest at +160.
The over/under is currently set at 50.0.
49ers vs. Eagles prediction Week 2
Winning back-to-back games on the road is never an easy task, even for the best of teams, and there are reasons to be concerned about the Niners, both in light of Verret’s injury and their late fourth-quarter near collapse.
That said, Philadelphia beat up on a lackluster Atlanta squad, and it’s impossible to look at San Francisco being anything but a pound-for-pound favorite over the restructuring Eagles at this point.
The 49ers have far more weaponry on offense, particularly at the skill positions, and those will ultimately prove to be the primary difference.
It might be another high-scoring affair, especially if the defense remains shorthanded within the secondary, but let’s ping the Niners as covering the spread with a 30-24 road win.
Next. 5 Niners who impressed most in Week 1 win vs. Lions. dark