San Francisco 49ers: 5 toughest quarterbacks Niners will face in 2020

Jimmy Garoppolo #10 of the San Francisco 49ers with Aaron Rodgers #12 of the Green Bay Packers (Photo by Sean M. Haffey/Getty Images)
Jimmy Garoppolo #10 of the San Francisco 49ers with Aaron Rodgers #12 of the Green Bay Packers (Photo by Sean M. Haffey/Getty Images) /
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Russell Wilson, Seattle Seahawks
Quarterback Russell Wilson #3 of the Seattle Seahawks (Photo by Thearon W. Henderson/Getty Images) /

49ers Opponent No. 1: Russell Wilson, Seattle Seahawks

Ah, yes. The bane of Niners fans’ existence everywhere the past 10 years: Russell Wilson.

Wilson joined Lamar Jackson and the Atlanta Falcons’ Matt Ryan as the only quarterbacks to beat San Francisco during the regular season last year. Yet Wilson’s pedigree as a perennial 49ers killer needs little introduction.

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But in case you forgot, Wilson owns a 12-4 record against his NFC West rivals, having tossed a combined 3,347 yards with 27 touchdowns (one rushing) against only nine interceptions and a passer rating of 97.9.

If there’s a small consolation, no other team in the NFL has sacked Wilson more than San Francisco (26 times), so perhaps that’ll be the goal again for Niners defensive coordinator Robert Saleh and Co. when both teams square off for their two-game series in 2020.

Fittingly enough, the 49ers host the Seahawks for a Week 17 finale which could again determine the outcome of the NFC West as it did a year ago.

On that final play in Seattle, Wilson’s pass to tight end Jacob Hollister ended up being completed just short of the goal line on fourth down, giving the win to San Francisco. But Niners fans everywhere wouldn’t have been shocked if Wilson once again pulled off yet another heartbreaking comeback over the red and gold.

Next. Ranking 49ers' 5 toughest games in 2020. dark

It’s happened so many times before. Hopefully, 2020 doesn’t see a replication of that trend.