49ers Jimmy Garoppolo is a must start vs. Seahawks in fantasy football Week 10

SANTA CLARA, CALIFORNIA - OCTOBER 07: Jimmy Garoppolo #10 of the San Francisco 49ers reacts after he threw a touchdown pass to George Kittle against the Cleveland Browns at Levi's Stadium on October 07, 2019 in Santa Clara, California. (Photo by Ezra Shaw/Getty Images)
SANTA CLARA, CALIFORNIA - OCTOBER 07: Jimmy Garoppolo #10 of the San Francisco 49ers reacts after he threw a touchdown pass to George Kittle against the Cleveland Browns at Levi's Stadium on October 07, 2019 in Santa Clara, California. (Photo by Ezra Shaw/Getty Images) /
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The undefeated San Francisco 49ers take on the Seattle Seahawks Week 10 on Monday Night Football in their biggest matchup of the season to date. In this matchup, quarterback Jimmy Garoppolo is a fantasy football must start.

On Monday Night Football, the San Francisco 49ers have their most important game to date against the Seattle Seahawks, their NFC West divisional rival. While the Niners are currently favored by six points, this should be an incredibly close and exciting game.

In this must-watch game, quarterback Jimmy Garoppolo is a fantasy football must start.

There are two factors making Garoppolo a fantasy must start for Week 10. The first is Garoppolo himself. Since the Niners traded for wide receiver Emmanuel Sanders, Garoppolo has looked like a completely different quarterback. He started out the season as more of a game manager, which he was fantastic at, directing the Niners run-heavy offense. But the addition of Sanders has allowed Garoppolo to show what he is truly capable of as a passer.

Last week against the Arizona Cardinals, Garoppolo had his best game of 2019, if not his career. He carved up the Arizona secondary to the tune of 317 passing yards, four touchdowns and 28.88 fantasy points. Garoppolo looked fantastic last week, and I’m not just talking about his jawline.

The point is Garoppolo is playing the best football of his career right now, and there is no reason to expect that to end this week. That brings us to the next reason Garoppolo is a fantasy football must start: The matchup.

The Seahawks have one of the best offenses in football. Their offensive success is due to one factor, quarterback Russell Wilson. Wilson, long seen as one of the NFL’s best quarterbacks, is currently playing the best football of his career. He is widely seen as the favorite to win the league MVP at this point.

Wilson is an incredible quarterback, playing better than he ever has. He will be able to score on the 49ers defense. I know that’s hard to hear but it’s true. The Niners defense is incredible, but last week, Cardinals rookie quarterback Kyler Murray threw for 241 yards and two touchdowns, ending the game with a passer rating of 130.7.

And while Murray is good, he’s no Wilson.

Many will attribute Murray’s success to the Niners simply having an off night, which is probably true, but it still shows that the Niners can be beat by opposing quarterbacks. And if there is any possibility of a defense being beat, Wilson will beat it.

Wilson will score on the 49ers defense, it’s inevitable. The Niners defense will certainly slow him down, but he will score. Because of this, Garoppolo will have to make plays to match him.

And luckily, he is playing at a level where he is prepared to do just that.

More important is the fact the Seattle defense is very vulnerable to having plays made against it. A major factor in Wilson’s offensive brilliance this season has been the need to bail out an atrocious Seattle defense. From a fantasy football perspective, Seattle has given up over 20 fantasy points to opposing quarterbacks in each of the past three weeks.

One of those quarterbacks was the Baltimore Ravens’ Lamar Jackson, another MVP favorite, so his success was to be expected.

But the other two performances came from the Michelangelo of turnovers, Jameis Winston of the Tampa Bay Buccaneers, and career backup Matt Schaub with the Atlanta Falcons. Clearly, the Seahawks defense is a great matchup for quarterbacks, fantasy wise. With Garoppolo playing at an elite level, in a matchup where he will likely be forced to throw, he should take full advantage of Seattle’s weakness and have a huge fantasy day.

Here’s a few other pieces of fantasy thoughts and advice:

  • Sanders is a must start this week as well. In only his second game with the Niners last week, he had over 20 fantasy points in PPR and half point PPR scoring systems. As he continues to familiarize himself with the Niners offense and build chemistry with Garoppolo, he should only become more valuable in fantasy. He should be one of the main beneficiaries of Seattle’s weak pass defense.
  • Tight end George Kittle is currently dealing with a knee injury suffered last week against the Cardinals, leaving his playing status in doubt. Kittle is always a fantasy must start when he plays, but make sure to monitor the situation and have a backup plan in place in the event he does not play, especially with the game on Monday night.
  • If you’ve been riding the roller coaster that is the 49ers run game in fantasy with me, don’t stop now. The Seahawks defense against the run is ranked 13th, but with the Niners likely to have some key run blockers returning from injury, their run game should be able to continue to succeed. With Matt Breida currently on the injury report with an ankle injury, Tevin Coleman is a must start as the lead back. Despite inconsistency, the fantasy potential of this run game is always too good to pass up. If Breida plays, he is always worth a look for at least a flex spot as well.

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The Niners’ Week 10 matchup against the Seahawks is must see TV. It also is a matchup full of opportunities to succeed in fantasy football. The biggest one is Garoppolo, who is primed for a huge game.

Start him, and reap the rewards on Monday night.