49ers vs. Colts: Full Week 5 preview for San Francisco

GLENDALE, AZ - OCTOBER 01: Defensive tackle DeForest Buckner #99 of the San Francisco 49ers hits quarterback Carson Palmer #3 of the Arizona Cardinals during the second half of the NFL game at the University of Phoenix Stadium on October 1, 2017 in Glendale, Arizona. (Photo by Norm Hall/Getty Images) /

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INDIANAPOLIS, IN – SEPTEMBER 17: An Indianapolis Colts fan celebrates in the first quarter of a game against the Arizona Cardinals at Lucas Oil Stadium on September 17, 2017 in Indianapolis, Indiana. (Photo by Joe Robbins/Getty Images) /

Game information

The 49ers and Colts kickoff at 10:00 a.m. and the game will be broadcasted on FOX.

For those who would like to live stream the game, you can follow this link: https://www.fubo.tv/watch/NFL?irad=356362&irmp=374356

Odds Shark currently has the Colts as favorites, with a predicted score of 26.4 to 15.9. The site has Indianapolis winning with the Colts covering the spread, and predict the total (45) will go under.

Next: 49ers film room: Why DeForest Buckner is so important in Week 5 vs. Colts

With an 0-5 start facing the 49ers, the desperation level is starting to tick upwards. A win against the Colts would stop that upward trend, and ease some of the anxiety building up around San Francisco.