Cardinals vs. 49ers: 5 Matchups in Week 5 to Watch for San Francisco

November 29, 2015; Santa Clara, CA, USA; General view of the line of scrimmage between the San Francisco 49ers and the Arizona Cardinals.Mandatory Credit: Kyle Terada-USA TODAY Sports
November 29, 2015; Santa Clara, CA, USA; General view of the line of scrimmage between the San Francisco 49ers and the Arizona Cardinals.Mandatory Credit: Kyle Terada-USA TODAY Sports /
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The San Francisco 49ers host the Arizona Cardinals for an NFC West showdown on Thursday Night Football. Niner Noise takes a look at five matchups to watch between these two 1-3 teams entering Week 5.

NFL: San Francisco 49ers at Arizona Cardinals. Mandatory Credit: Mark J. Rebilas-USA TODAY Sports
NFL: San Francisco 49ers at Arizona Cardinals. Mandatory Credit: Mark J. Rebilas-USA TODAY Sports /

Who would have thought the Arizona Cardinals would have a 1-3 record heading into their Week 5 matchup against the San Francisco 49ers?

But that’s exactly what the reigning NFC West champions have. 2016 has been weird for plenty of teams around the NFL, and it’s strange to say the Niners (1-3) are higher than the Cardinals in the division.

San Francisco owns the tie-breaker, by the way.

Irregardless of the record, the 49ers and Cardinals will square off at Levi’s Stadium on October 6 for Thursday Night Football.

TNF games aren’t always pretty. And it’s no surprise Odds Shark listed Arizona as four-point favorites.

Arizona is struggling though, especially on offense. And with Cardinals quarterback Carson Palmer (concussion) potentially out, will the 49ers be able to stage an upset?

If they do, the following five matchups will be reasons why.

Let’s look at these matchups and try to determine how San Francisco can upend its division rival at home.