Predicting Every 49ers Game in 2016
![Sep 1, 2016; San Diego, CA, USA; 49ers head coach Chip Kelly looks on from the sideline during the second half of the game against the San Diego Chargers at Qualcomm Stadium. San Francisco won 31-21. Mandatory Credit: Orlando Ramirez-USA TODAY Sports Sep 1, 2016; San Diego, CA, USA; 49ers head coach Chip Kelly looks on from the sideline during the second half of the game against the San Diego Chargers at Qualcomm Stadium. San Francisco won 31-21. Mandatory Credit: Orlando Ramirez-USA TODAY Sports](https://images2.minutemediacdn.com/image/upload/c_fill,w_720,ar_16:9,f_auto,q_auto,g_auto/shape/cover/sport/4e7422f60220943cef6e23f831d7215721331c7b41f4df2774834833ea75115e.jpg)
Week 5 vs. Arizona Cardinals – LOSS
The 49ers were unfortunate not to claim a shock home win over the Cardinals in 2015, a series of questionable decisions going against them in a 19-13 defeat.
However, this is a Cardinals team that has improved again, with a defense that has little regard for the 49ers offense, bolstered by the additions of Chandler Jones and Robert Nkemdiche.
This game comes on another short week for the 49ers, and the defense figures to be especially tired having been tested by a talented Cowboys team.
Expect the Cardinals to take advantage and record a Thursday night victory.
Next: Week 6 @ Buffalo Bills