Niner Noise
FanSided

Predicting Every 49ers Game in 2016

By Nicholas McGee

Sep 1, 2016; San Diego, CA, USA; 49ers head coach Chip Kelly looks on from the sideline during the second half of the game against the San Diego Chargers at Qualcomm Stadium. San Francisco won 31-21. Mandatory Credit: Orlando Ramirez-USA TODAY Sports
Sep 1, 2016; San Diego, CA, USA; 49ers head coach Chip Kelly looks on from the sideline during the second half of the game against the San Diego Chargers at Qualcomm Stadium. San Francisco won 31-21. Mandatory Credit: Orlando Ramirez-USA TODAY Sports /
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Aug 20, 2016; Orchard Park, NY, USA; Buffalo Bills quarterback Tyrod Taylor (5) is chased by New York Giants defensive end Olivier Vernon (54) from the pocket during the first half at New Era Field. Mandatory Credit: Kevin Hoffman-USA TODAY Sports
Aug 20, 2016; Orchard Park, NY, USA; Buffalo Bills quarterback Tyrod Taylor (5) is chased by New York Giants defensive end Olivier Vernon (54) from the pocket during the first half at New Era Field. Mandatory Credit: Kevin Hoffman-USA TODAY Sports /

Week 6 @ Buffalo Bills – LOSS

San Francisco will at least have plenty of time to prepare for another cross-country trip this time. But the Kelly skeptics will start to make their voices heard after defeat in Orchard Park.

This will be something of a revenge game for Bills offensive coordinator Greg Roman, who was one of the scapegoats in the 49ers final season under Jim Harbaugh.

Roman’s attack, led by Tyrod Taylor, LeSean McCoy and Sammy Watkins, should prove too much for what is likely to be an up-and-down defense struggling to deal with the 10 a.m. PST start as the Niners drop to 2-4.

Next: Week 7 vs. Tampa Bay Buccaneers