Lions vs. 49ers opening odds for NFC Championship Game (San Francisco heavily favored)

The San Francisco 49ers are heavily favored to advance to Super Bowl 58 when they take on the Detroit Lions in the NFC Championship Game.

San Francisco 49ers running back Christian McCaffrey (23).
San Francisco 49ers running back Christian McCaffrey (23). / Dan Powers-USA TODAY Sports

The matchup for the NFC Championship Game is set!

The San Francisco 49ers will take on the Detroit Lions after Jared Goff and company knocked off the Tampa Bay Buccaneers on Sunday afternoon. 

The 49ers, who escaped a tough No. 7-seeded Green Bay Packers team on Saturday night, will host Detroit in the NFC Championship Game. 

San Francisco enters this game not only as the favorite to win the title in the latest Super Bowl odds, but the team is also heavily favored to win against the Lions and advance to Super Bowl 58. 

The 49ers did not cover the spread in their win over the Packers, but fans and bettors have to like that oddsmakers view the 49ers as a touchdown favorite in this game. 

Here’s a look at the opening odds, courtesy of FanDuel Sportsbook. 

If you want to bet on this game, take advantage of FanDuel’s amazing promo offer. New users that sign up with the link below will receive $150 in bonus bets if they simply place a $5 wager! That’s a great way to bet on the NFC title game. 

Lions vs. 49ers opening odds, spread and total

49ers set as sizeable favorites in NFC Championship Game

San Francisco has an implied probability of 76.19 percent to win the NFC Championship Game based on the opening moneyline odds of -320. 

The 49ers have been solid at home this season, going 6-3 straight up (including playoffs), but they are just 3-6 against the spread as home favorites. 

Bettors may want to proceed with caution with laying seven points on San Fran in this game, especially after the team struggled a bit without Deebo Samuel in the divisional round. Still, oddsmakers clearly expect the 49ers to advance to the Super Bowl for the second time in the Kyle Shanahan era. 

Odds to win Super Bowl 58

The 49ers are the favorite to win Super Bowl 58, a great sign for their chances of taking down Detroit in Santa Clara on Sunday. 

If you want to wager on the 49ers to go all the way, it may be more lucrative than taking them on the moneyline against Detroit and in the Super Bowl, as it’s possible the 49ers are favored in both games – should they win against the Lions.

Odds refresh periodically and are subject to change.

Find Peter Dewey's betting record here.