49ers Odds to Win Super Bowl 59 (San Francisco Favored to Win in 2025)

The San Francisco 49ers are the favorite in the opening odds to win Super Bowl 59.

San Francisco 49ers quarterback Brock Purdy (13) throws a pass.
San Francisco 49ers quarterback Brock Purdy (13) throws a pass. / Mark J. Rebilas-USA TODAY Sports

The 2023 NFL season ended in heartbreak for the San Francisco 49ers, coming up short in overtime against the Kansas City Chiefs in Super Bowl 58. 

For 49ers fans, there is still a lot to look forward to with this team – led by young star quarterback Brock Purdy, who played well in Super Bowl 58. 

Oddsmakers think that this won’t be the last time that Purdy and this 49ers group makes the Super Bowl, as the team is set as the favorite to win the Super Bowl next season.

While that doesn’t guarantee anything, as the 49ers were the favorite for a large chunk of the 2023 season and the entire playoffs, it is a good sign for the team’s outlook next season. 

49ers Super Bowl Odds 2025

San Francisco comes in at +450 odds, meaning that there is an implied probability of 18.18 percent that the 49ers will hoist the Lombardi Trophy at the end of next season. 

Could it be worth taking the team now in the betting market? 

Oddsmakers clearly are expecting the AFC to be a tough conference to navigate in the latest odds with the Kansas City Chiefs, Baltimore Ravens, Buffalo Bills and others sitting at +750 or worse odds to win it all. 

In a weaker conference with a division that is certainly winnable, the 49ers could find themselves right back on the NFL’s brightest stage next season. 

If you want to take a chance on the 49ers to win Super Bowl 59, you can do so at FanDuel Sportsbook! New users that sign up with the link below will receive $200 if they wager $5 and their first bet wins!

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Odds refresh periodically and are subject to change.