5 biggest concerns 49ers have through two weeks of 2021

No. 1: Injury attrition is a thing for 49ers… again

Let’s all simply hope whatever injury challenges the Niners face in 2021 won’t come anywhere near as close as what was dealt with last season.

Early this year, though, the injury problems have already been substantial enough.

Raheem Mostert’s loss is bad enough, as he was expected to produce sizable numbers in a contract year. But one could make the argument that San Francisco’s loss of No. 1 cornerback Jason Verrett to a season-ending ACL tear could haunt the team even more over the rest of the season.

Related Story: The curious case of 49ers’ cornerback situation

True, Deommodore Lenoir’s emergence has helped offset Verrett’s loss to a certain extent. Yet the problems are again compounded by the fact fellow corner Emmanuel Moseley has been inactive two weeks already with a knee injury of his own.

Thus, forcing the 49ers to scramble for free-agent contingency options like Josh Norman, who was flagged for two defensive pass-interference calls in Week 2, and Dre Kirkpatrick.

Linebacker Dre Greenlaw is out multiple weeks with a groin injury, and the Niners have already been challenged to test their depth behind him, too.

The 2-0 record suggest San Francisco has done enough to overcome these setbacks, but having to test the depth so early this season could bring forth even more problems in the coming weeks.