49ers: First-take regular-season schedule predictions for 2018

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SANTA CLARA, CA – NOVEMBER 26: Quarterback Russell Wilson #3 of the Seattle Seahawks calls a play a the line of scrimmage against the San Francisco 49ers at Levi’s Stadium on November 26, 2017 in Santa Clara, California. (Photo by Lachlan Cunningham/Getty Images) /

Week 15 vs. Seattle Seahawks

These two teams will be pretty familiar with each other by the time Week 15 rolls around, and the edge still goes to the 49ers here.

While the Week 13 prime-time storyline will focus mostly on Richard Sherman and his return to Seattle, Week 15 will focus more on how the Seahawks have relinquished control of the division and have fallen behind San Francisco in the division’s power rankings.

Jimmy Garoppolo’s efforts will be more than enough to overcome a Seahawks defense lacking star power this season.

And while there could be some heroics from Russell Wilson on the other side, it certainly won’t be enough to make the difference.

The Niners sweep the season series with Seattle for the first time since 2011.

San Francisco 49ers: First-take regular-season schedule predictions for 2018

By Peter Panacy | Apr 20, 2018

Week 15 vs. Seattle Seahawks

Prediction: 49ers 21, Seahawks 14