49ers vs. Cardinals: Previewing Week 10 for San Francisco

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November 29, 2015; Santa Clara, CA, USA; General view of a NFL football on top of an end zone pylon before the game between the San Francisco 49ers and the Arizona Cardinals at Levi’s Stadium. The Cardinals defeated the 49ers 19-13. Mandatory Credit: Kyle Terada-USA TODAY Sports
November 29, 2015; Santa Clara, CA, USA; General view of a NFL football on top of an end zone pylon before the game between the San Francisco 49ers and the Arizona Cardinals at Levi’s Stadium. The Cardinals defeated the 49ers 19-13. Mandatory Credit: Kyle Terada-USA TODAY Sports /

Game Information

San Francisco and Arizona kick off Week 10 on Sunday, November 13 at 4:25 p.m. ET at University of Phoenix Stadium.

Here’s the breakdown, from FanSided:

Date: Sunday, November 13, 2016
Start Time: 4:25 p.m. ET
Location: Glendale, AZ
Venue: University of Phoenix Stadium
TV Info: FOX
Live Stream: NFL Sunday Ticket

It doesn’t take a genius to figure out the Niners aren’t favored in this one. According to Odds Shark, the 49ers are 13.5-point underdogs with a predicted score of 35.8 to 10.2 in favor of the Cardinals.

More from Niner Noise

For San Francisco to win, almost everything would have to go right and the Niners would have to play mistake-free football — something they couldn’t do a week ago.

And Arizona would have to suffer more than its fair share of on-field gaffes.

This isn’t a likely scenario. So we shouldn’t come close to expecting any sort of NFC West upset here.

Next: 5 49ers Who Should See More Playing Time

We’ll roll with that prediction. The 49ers are going to lose this game. The only question is just how big an embarrassment it will be.