Predicting Every 49ers Game in 2016

Sep 1, 2016; San Diego, CA, USA; 49ers head coach Chip Kelly looks on from the sideline during the second half of the game against the San Diego Chargers at Qualcomm Stadium. San Francisco won 31-21. Mandatory Credit: Orlando Ramirez-USA TODAY Sports
Sep 1, 2016; San Diego, CA, USA; 49ers head coach Chip Kelly looks on from the sideline during the second half of the game against the San Diego Chargers at Qualcomm Stadium. San Francisco won 31-21. Mandatory Credit: Orlando Ramirez-USA TODAY Sports /
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Sep 1, 2016; East Rutherford, NJ, USA; New England Patriots quarterback Tom Brady (12) before game against New York Giants at MetLife Stadium. Mandatory Credit: Noah K. Murray-USA TODAY Sports
Sep 1, 2016; East Rutherford, NJ, USA; New England Patriots quarterback Tom Brady (12) before game against New York Giants at MetLife Stadium. Mandatory Credit: Noah K. Murray-USA TODAY Sports /

Week 11 vs. New England Patriots – LOSS

San Francisco does have some things in its favor in this matchup. The Patriots will making a cross-country trip on the back of a tough home clash with the Seahawks, and Chip Kelly got the better of Bill Belichick last season.

But, playing in a stadium 25 miles from his hometown of San Mateo – and on a personal revenge mission after serving his four-game ban – it is extremely difficult to bet against Tom Brady and the Patriots.

New England rolls and the 49ers drop to 4-6.

Next: Week 12 @ Miami Dolphins