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San Francisco 49ers: Full Win/Loss Predictions for All 16 Games

By Bobby Horne

January 20, 2016; Santa Clara, CA, USA; Chip Kelly poses for a photo after being introduced as the new head coach for the San Francisco 49ers at Levi's Stadium Auditorium. Mandatory Credit: Kyle Terada-USA TODAY Sports
January 20, 2016; Santa Clara, CA, USA; Chip Kelly poses for a photo after being introduced as the new head coach for the San Francisco 49ers at Levi's Stadium Auditorium. Mandatory Credit: Kyle Terada-USA TODAY Sports /
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Nov 22, 2015; Seattle, WA, USA; Seattle Seahawks running back Thomas Rawls (34) scores a touchdown during the fourth quarter in a game against the San Francisco 49ers at CenturyLink Field. The Seahawks won 29-13. Mandatory Credit: Troy Wayrynen-USA TODAY Sports
Nov 22, 2015; Seattle, WA, USA; Seattle Seahawks running back Thomas Rawls (34) scores a touchdown during the fourth quarter in a game against the San Francisco 49ers at CenturyLink Field. The Seahawks won 29-13. Mandatory Credit: Troy Wayrynen-USA TODAY Sports /

Week 3

When: Sunday, September 25th

Who: Seattle Seahawks

Where: CenturyLink Field

Round one with the Seahawks.

The fact of the matter is, the 49ers can not get things right against Seattle. In their last five meetings, the 49ers have not won any of them. Seattle is an elite team and they don’t show any signs of slowing down. This is a tough matchup for the 49ers.

Key Matchup: Any of Seattle’s Running Backs vs. 49ers Defensive Line

Last time these two teams met, Seattle running back Thomas Rawls gashed the 49ers defense for 255 all-purpose yards and two touchdowns. Look for much of the same this week.

Prediction: Loss

Next: Week 4