The San Francisco 49ers will host the Pittsburgh Steelers in their final home game of the regular season. It will also be the first and only Monday Night Football game for the Niners. It is a great match up between two historical franchises. The game will be a hard hitting affair as we got two of the best defenses in the NFL squaring off against one another. Both teams will be without their defensive leaders. LB Patrick Willis is listed as questionable for the second straight game and it is a safe bet that he will not be suited up for the game. LB James Harrison will also be out for the game due to a one game suspension for a helmet to helmet hit on Cleveland Browns QB Colt McCoy. This is a huge game for both teams when it comes to playoff positioning. The Niners need a win in order to achieve the second seed and get a first round bye in the NFC playoffs. The Steelers are still fighting out with the Baltimore Ravens for the AFC North title and as well for a possible first round bye in the AFC playoffs. Here are some keys for this great matchup of two Super Bowl contending teams. (more…)