49ers vs. Panthers: Previewing Week 2 for San Francisco

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The San Francisco 49ers face a tough challenge as they take to the road to battle the Carolina Panthers in Week 2. Niner Noise breaks down this contest and points out who’s worth watching, X-factors and much more.

NFL: Divisional Round-San Franciso 49ers at Carolina Panthers. Mandatory Credit: Sam Sharpe-USA TODAY Sports
NFL: Divisional Round-San Franciso 49ers at Carolina Panthers. Mandatory Credit: Sam Sharpe-USA TODAY Sports /

The San Francisco 49ers won’t have an easy task in Week 2 as they square off against the reigning NFC champions, the Carolina Panthers, on Sunday, September 18 at 1 p.m. ET.

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  • San Francisco demolished the Los Angeles Rams 28-0 on Monday Night Football in Week 1. But the Niners are also traveling east on a short week to take on a well-rested Panthers team that lost 21-20 to the Denver Broncos on September 8.

    The 49ers would still be facing a near impossible task trying to knock off the Panthers at home. The short week, plus travel, makes this challenge even more difficult.

    Carolina is nothing like the Rams. Led by last year’s MVP, quarterback Cam Newton, the Panthers offense is vastly superior to what the Niners encountered in Week 1.

    And Carolina’s defense, especially the front seven, remains one of the league’s elite.

    So it shouldn’t be much of a surprise the Panthers opened up as 13.5-point favorites, according to Odds Shark.

    Does this mean we should rule out a San Francisco victory? Or should we simply hope for a hard-fought, close game in which the 49ers prove to the rest of the NFL world they’re better than what many perceive them to be?

    Niner Noise breaks down this Week 2 bout and looks at what factors make up this contest.

    Next: Week 2 By the Numbers